Scientists across Africa are intensifying research into innovative methods to curb malaria transmission, as the continent falls behind the African Union target of eliminating the disease by 2030.
Working under the Target Malaria initiative, researchers are investigating the use of gene drive technology to either reduce populations of malaria-carrying mosquitoes or block the transmission of the parasite from insects to humans.
The approach represents a shift toward genetic solutions that could complement existing interventions such as insecticide-treated bed nets, antimalarial drugs, vaccines, and indoor spraying.
According to a publication by the African Media Agency, the renewed push for innovation comes amid a widening global funding gap and increasing challenges confronting malaria control efforts.
These include growing insecticide resistance, climate-related pressures, and weak health systems in several countries, factors experts warn could reverse gains made over the past decade if not urgently addressed.
The report noted that progress in reducing malaria cases has slowed significantly since 2015, with only a few countries meeting key reduction milestones, leaving Africa off track to meet its elimination goal.
Scientists involved in the initiative say gene drive technology could serve as a complementary tool, rather than a replacement, strengthening current prevention strategies and improving long-term outcomes.
They emphasised the need for sustained investment, research, and cross-border collaboration to ensure that new innovations are safely developed and effectively deployed in the fight against malaria.
